Rhobin Keeps Abreast

Revelations from fluorescent imaging – highlighting specific biomolecules with a glowing tag – underpin a whole host of biomedical discoveries (have a peruse of BPoD's sumptuous 15-year archive to see for yourself), but improvements to optimise the tags are constantly being sought, especially for the more stringent requirements of live-cell imaging. Here, researchers have designed and engineered proteins that bind to rhodamine fluorophores (calling the approach Rhobin) which enable bright, reversible, stable labelling of live or fixed cells, even at high temperatures (making them suitable for live study of extremophiles!)

Read the published research article here

Written by Lindsey Goff

Lindsey Goff

Editor-in-Chief

Formerly immunologist for Cancer Research UK, Lindsey has since moved into the field of scientific publishing. She looks after all BPoD editorial matters.

• Image from work by Yuda Chen, Klaus Yserentant and Kibeom Hongand, colleagues
• Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA
• Image originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)
• Published in Cell, September 2026