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04 August 2026
Entry by PROX1
Lymphatic vessels are not meant grow in the brain, but they are found in brain tumours such as glioblastoma or when there are brain vessel malformations, where they can cause disruption of the blood-brain barrier. In this study, researchers identify aberrant activity of the PROX1 gene in lymphatic vessel cells as a key that allows them to venture into the usually prohibited tissue
Read the published research article here
Written by
- Image from work by Sara González-Hernández and colleagues
- Laboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Journal of Clinical Investigation inSIGHT, January 2026
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