Exploring Caves

Our cell membranes are complex structures vital for all functions – including reshaping, enabling transport of molecules to communicate and to activate signals. In the membrane is a dynamic scaffold of proteins, the main component of which is caveolin 1, creating invaginations called caveolae ('little caves') that underlie the cell's functions. Here, the biophysical mechanisms leading to the formation of these caveolin 1 complexes are interrogated by simulations and modelling, revealing that remodelling arises collectively from the coordinated action of multiple complexes

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Written by Lindsey Goff

Lindsey Goff

Editor-in-Chief

Formerly immunologist for Cancer Research UK, Lindsey has since moved into the field of scientific publishing. She looks after all BPoD editorial matters.

• Video from work by Korbinian Liebl & Gregory A. Voth
• Department of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL, USA
• Video originally published with a Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 4.0)
• Published in Nature Communications, July 2026