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07 October 2026

Making Absence Grow

Creating something that's not there and yet is vital sounds like a conundrum. Tubes and sacs of the body's organs and transport highways share such a feature: an absence of tissue in the middle – a lumen – but how is this initiated and formed? Here, using computer modelling in pancreatic organoids – lab-grown developing pancreas in miniature – this study reveals the pressures and processes leading to lumen formation (in blue)

Read the published research article here

Written by Lindsey Goff

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What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.