In the body, connective tissue connects – no news there. But how the right type develops in the right place continues to intrigue. Tendons are a type of connective tissue bringing muscle and bone together, and ligaments are a kind of highly-related connective tissue but distinctive, joining bone to bone. This study of zebrafish face development, identifies the genetic and epigenetic regulatory mechanisms that distinguish tendons and ligaments, and provides insight into disorders in which connective tissue turns to bone
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