We need trace metals for healthy cell function but then so do all other organisms, handily we have a means of safeguarding the supply of certain metals which doubles as an anti-pathogen strategy. A protein in the mammalian gut lining cells called natural resistance-associated macrophage protein 2 (also known as SLC11A2) starves pathogenic microrganisms of iron and manganese – shown here using Salmonella enterica (in red) as a model in cow gut, with metals tracked using fluorescent sensors
Read the published research article here
Written by
BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.