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22 March 2026
Signal to Sever
Cells' inner scaffolding, the cytoskeleton, is composed of many different proteins working in harmony as a lattice to accommodate the cell's movement and shape-changing needs. Microtubules (polymers of tubulin) are a major cytoskeletal component and they're regulated by enzymes that prune their length and growth. This study finds the enzyme spastin responds to lattice instability caused by microtubule defects as a signal to sever microtubules
Read the published research article here
Written by
- Video from work by Cordula Reuther and Paula Santos-Otte, and colleagues
- B CUBE – Center for Molecular Bioengineering, TUD Dresden University of Technology, Dresden, Germany
- Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Journal of Cell Science, March 2026
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