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09 February 2026
Developing Organoid Screen
Miniature lab-grown organ models known as organoids have revolutionised research because the fate of their component cells can be easily tracked or manipulated at a genetic/molecular level. Here, organoids undergo image-based high-content screening for molecular signals regulating their development. Studying human pancreas development identified 54 factors that shape features in the organoids, as well as pathways controlling one particular pancreas component – acinar cells (thought to underlie the most common form of pancreatic cancer)
Read the published research article here
Written by
- Image from work by Rashmiparvathi Keshara, Karolina Kuodyte and Antje Janosch, and colleagues
- Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Saxony, Germany
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Cell Stem Cell, February 2026
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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