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23 October 2026
Eye on Fat
Cell energy production from lipids involves a complex process across membranes of different organelles (the cell's 'organs' each with a vital function). By combining a microscopy technique called single-shot stimulated emission depletion-fluorescence lifetime imaging (STED-FLIM) with Nile Red fat-staining-dyes and deep learning–based analysis researchers were able to capture the process by simultaneously imaging the endoplasmic reticulum, mitochondria and lipid droplet organelles of live cells
Read the published research article here
STED-FLIM imaging was performed on a Leica Microsystems TCS SP8 STED 3× system
Written by
- Still from a video from work by Lu Gao & Beibei Gao, and colleagues
- Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China
- Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Science Advances, September 2026
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